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Model Characteristics - Model: Embryonal Rhabdomyosarcoma (Myf6Cre, p53)  
Model Descriptor Embryonal Rhabdomyosarcoma (Myf6Cre, p53)
Official Nomenclature
Genotype Myf6(ICNm/WT) p53(F2-10/F2-10)
Species Mouse (Mus musculus)
Strain Not specified 
Is This a Tool Strain? No
Developmental Stage
(applies only to Zebrafish)
 
Experimental Design Three allele mouse model of the classical young childhood muscle cancer, embryonal rhabdomyosarcoma, for use in basic science and translational studies.  
Phenotype This transgenic mouse model develops embryonal rhabdomyosarcoma at the age of 4 - 16 months (median 12 months) without injury.
Website for add. info  
Breeding Notes

 

Sex Distribution of the Phenotype Both Sexes 
Submitted by Keller, Charles
Principal Investigator / Lab Keller, Charles
Comment  
 
Model Availability: This model is available from
Strain Distributor Stock number
Myf6-ires-cre knock-in  NCI Mouse Repository 01XBL   
p53 floxed  NCI Mouse Repository 01XC2   
 
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